Punk rockers Against Me! will release their sixth album, Transgender Dysphoria Blues, on January 21. It will be the first record the group has released since frontwoman Laura Jane Grace told Rolling Stone that she was transitioning her gender to a woman in May 2012. Accordingly, the album's lyrical content will deal intimately with transgender dysphoria, a clinical term for feeling discontent with one's sex, as well as the loss of a friend, self-discovery, love and acceptance.

In addition to Grace's confessional lyrics, the record will feature a guest appearance by NOFX frontman Fat Mike, who plays bass on the songs "Unconditional Love" and "FUCKMYLIFE666." The group recorded the album at Dave Grohl's Studio 606, their own Total Treble Studio and a few other locations with engineer Billy Bush (Garbage, Muse).